The Strikers' win and additional bonus point saw them leapfrog their opponents into third spot on a congested table.
Strikers batsmen Alex Carey (29), Jake Weatherald, Phil Salt and Travis Head (31 each) all made starts, while Thunder quick Adam Milne claimed 1/6 from four overs to play a role in restricting the Strikers to 6/159.
In reply, the Thunder were cruising at 1/71 after nine overs, with Usman Khawaja and Callum Ferguson seemingly in control of the chase.
Strikers bowlers Peter Siddle (2/22, four overs) and Michael Neser (2/7, three overs) impressed, and Jake Weatherald took a one-handed screamer at backward point to remove Thunder X-Factor Alex Ross (18).
Neser was a highlight, almost achieving a hattrick when consecutive deliveries dismissed Khawaja (36) and Ferguson (22), as both failed to cash in on their positive starts.
Liam O’Connor couldn’t be kept out of the action, first running out Sam Billings off his own bowling, before claiming the wicket of Chris Green (4).
Late hitting from Ben Cutting (24 not out) and injured tailender Daniel McAndrew (17 not out) gave the Thunder a sniff but they ultimately fell short, posting 7/153 from their 20 overs.
The same teams meet again at the same venue on Monday to wrap up their regular-season commitments.